Laboratory Billing

Lab Billing That
Survives an LCD Audit.

Lab billing looks simple until PAMA rate cuts, panel bundling rules, and LCD coverage restrictions collide — bill a component separately when a panel code applies, or run a molecular test without a covered ICD-10 code, and you're looking at a compliance violation, not just a denial.

80047/80048
BMP codes that must bill as a panel, not components
1,000s
Claims where small PAMA rate gaps compound into material revenue loss
81105-81479
Molecular/genomic code range flagged as an OIG audit magnet
98.4%
Clean claim rate

Common Billing Challenges

Where Laboratory Billing Revenue Gets Lost

These are the six billing failure points we see most often in laboratory practices — and the ones our team resolves systematically from day one.

📊

Panel Unbundling

Billing the individual components of a Basic Metabolic Panel (80047/80048) separately to capture higher reimbursement instead of the panel code is a compliance violation, not a coding preference.

💲

PAMA Rate Drift

Clinical Lab Fee Schedule rates are benchmarked against private payer data and phased in over multiple years — labs that aren't tracking their top-billed codes against the current CLFS are absorbing a rate cut quietly.

🧬

Molecular Testing Coverage Gaps

Tier 1 and Tier 2 molecular pathology and genomic sequencing codes (81105-81479) are audit magnets; every claim needs a documented clinical indication tied to a covered ICD-10 code.

📝

Missing ABN Documentation

When Medicare won't cover a test under LCD criteria, you need an ABN before running it — without one, a denial means the cost is the lab's, not the patient's.

🔁

Reflex Testing Authorization Gaps

A reflex test triggered automatically off a first result still needs its own billing support and a standing order that covers it — you can't bill a reflex test that wasn't authorized.

🏢

CLIA Certificate Mismatches

Physician offices with a CLIA waiver can only bill waived-complexity tests; billing moderate-complexity codes on a waived certificate is a compliance issue, not a simple denial.

Key Procedure Codes

High-Value CPT & HCPCS Codes We Optimize for Your Lab

Our coders hold specialty-specific credentials and train continuously on the codes that drive the most revenue — and the most denials — in laboratory billing.

CPT/HCPCS CodeDescriptionCommon Issue
80047 / 80048Basic Metabolic PanelMust bill as a panel when all components are run — not individually
81105-81479Molecular pathology, Tier 1 / Tier 2Requires documented clinical indication tied to a covered ICD-10 code
BRCA / pharmacogenomic panelsGenetic testing codesTight NCD coverage restrictions; verify before running the test
ABNAdvance Beneficiary NoticeRequired before running a test that doesn't meet LCD criteria
Reflex test codesAuto-triggered follow-up testingNeeds a standing order or advance authorization to be billable

Why Rcmaxis

Purpose-Built for Laboratory Billing

We're not a generalist billing service that added a specialty module. Our team is built around specialty-specific expertise.

01

Specialty-Credentialed Coders

Every coder on your account holds the specialty coding credential relevant to laboratory services — not a generic CPC only.

02

98.4% Clean Claim Rate

Significantly above the denial patterns lab practices see from LCD mismatches and panel unbundling. Fewer rejections means faster payment and less write-off risk.

03

2-Week Onboarding

Full EHR integration, payer enrollment verification, and charge capture setup in 2 weeks — with zero disruption to your surgical schedule.

04

Dedicated Account Manager

One point of contact who knows your practice, your payers, and your billing history — available for weekly calls and monthly performance reviews.

05

No Long-Term Contracts

Month-to-month engagement. We earn your business every month by improving your collections — not by locking you in.

06

Real-Time Dashboards

Live visibility into your collections, denial rate, aging AR, and payer performance — updated daily, reviewed monthly with your account team.

Common Questions About Laboratory Billing

Straight answers to what practices usually ask before they switch.

No. If you run all the components of a panel like the Basic Metabolic Panel (CPT 80047 or 80048), you're required to bill the panel code — not each individual test separately. Billing the components individually to get higher reimbursement is called unbundling and is a compliance violation, not just a billing preference.
An Advance Beneficiary Notice (ABN) is needed when you know Medicare won't cover a test — because the diagnosis doesn't meet LCD criteria, or the test is non-covered — before you run it. The ABN transfers financial responsibility to the patient. Without it, if Medicare denies the claim, you can't bill the patient and the cost is the lab's.
Molecular pathology and genomic sequencing codes (Tier 1 and Tier 2, CPT 81105-81479) are audit magnets because coverage depends heavily on documented medical necessity. Every claim should have a documented clinical indication tied to a covered ICD-10 code before submission — genetic testing categories like BRCA and pharmacogenomics carry especially tight NCD restrictions.
Only if there's a standing order that covers the reflex test in advance. Reflex testing — where a second test automatically runs based on the first result — needs to be ordered ahead of time or covered by a standing order; you can't bill a reflex test that wasn't authorized, even if it was triggered automatically by the lab's protocol.

See what your laboratory is leaving on the table.

Free revenue assessment for qualified practices. We audit your last 90 days of claims, identify every revenue leak, and show you a clear path to better collections — at no cost.

Claim Your Free Audit

Related Resources

Full Laboratory Billing GuideSpecialty Clinic BillingFree Revenue AssessmentReal Practice Results